Research

Research Projects in Biomedical Imaging Lab

1. Fluorescence molecular tomgoraphy (FMT) for small animal imaging

Yue Zhao, Dianwen Zhu, Beikejiang Reheman, Changqing Li, “3D mouse shape reconstruction based on phase-shifting algorithm for fluorescence molecular tomography imaging system”, Applied Optics, 54, 9573-9582 (2015).
 
Dianwen Zhu, Changqing Li, "Nonuniform update for sparse target recovery in fluorescence molecular tomography accelerated by ordered subsets", Biomedical Optical Express, 5, 4249-4259 (2014).
 
Dianwen Zhu, Changqing Li, "Nonconvex regularizations in fluorescence molecular tomography for sparsity enhancement", Physics in Medicine and Biology, 59, 2901 (2014).
 
Li CQ, Mitchell GS, Dutta J, Ahn S, Leahy RM, Cherry SR, “A three-dimensional multispectral fluorescence optical tomography imaging system for small animals based on a conical mirror design”, Optics Express, 17 (9), 7571-7585 (2009). 
 

2. X-ray luminescence computed tomography (XLCT) and microCT for small animal imaging

Changqing Li, Arnulfo Mertinez-Davalos, Simon R. Cherry, “Numerical simulation of x-ray luminescence optical tomography for small animal imaging”, Journal of Biomedical Optics, 19, 4, 046002 (2014).
 
Changqing Li, Kun Di, Julien Bec, Simon R. Cherry S, “X-ray luminescence optical tomography imaging: experimental studies”, Optics Letters, 38, 2339-2341 (2013).
 

3. Cerenkov luminescence imaging and applications

Li CQ, Mitchell GS, Cherry SR, "Cerenkov luminescence tomography for small animal imaging", Optics Letters, 35, 1109-111 (2010)
 
Robertson R, Germanos MS, Li CQ, Mitchell GS, Cherry SR, and Silva MD, "Optical imaging of Cerenkov light generation from positron-emitting radiotracers," Phys Med Biol 54, N355-N365 (2009). 
 

4. Simultaneous FMT and positron emission tomography (PET) imaging for small animal

Li CQ, Yang YF, Mitchell GS, Leahy RM, Cherry SR, "Simultaneous PET and multispectral 3-dimensional fluorescence optical tomography imaging system", J. Nuclear Medicine, 52, 1268-1276 (2011)
 
 
Li CQ, Wang GB, Qi JY, Cherry SR, "Three-dimensional fluorescence optical tomography in small-animal imaging using simultaneous positron-emission-tomography priors", Optics Letters, 34, 2933-2935 (2009).